The alkaloid cytisine is the active ingredient of the drug, has a H-cholinomimetic action; ons ganglia of the autonomic nervous system, reflex stimulates the respiratory center, causes the release of adrenaline from the adrenal medulla increases blood pressure.
Tsitizin has much lower toxicity and a large winstrol results therapeutic index, with its mechanism of action is similar to the mechanism of action of nicotine. Tsitizin competitively inhibits the interaction of nicotine with the respective receptors, which leads to a gradual decrease and extinction of nicotine addiction.
Indications for use
Nicotine addiction (to facilitate smoking cessation).
Hypersensitivity to the active, or any of the excipients of the preparation, acute myocardial infarction, unstable angina, cardiac arrhythmia, recent myocardial ischemic attack, atherosclerosis, pregnancy and lactation, children under 18 and adults over 65 years, the lack of lactase, galactosemia, syndrome winstrol results mapabsorbtsii glyukozy- galactose (lactose included in the drug).
In patients with coronary heart disease, heart failure, hypertension, cerebral vascular disease, obliterating arterial diseases, hyperthyroidism, peptic ulcer, diabetes mellitus, renal or hepatic failure, some forms of schizophrenia, chromaffin adrenal tumors, gastroesophageal reflux disease.
Pregnancy and lactation
Not apply during pregnancy and during breastfeeding.
Dosage and administration
The tablets are taken orally whole, drinking plenty of fluids. The drug is used as follows: 1 to Day 3 – 6, 1 tablet every day, every 2 hours gradually reducing the number of cigarettes smoked. If the result is unsatisfactory, treatment is stopped, and after 2-3 months, you can start it again. With good effect of treatment continues as follows:
4 to 12 day of admission – 1 tablet 5 times a day, every 2.5 hours;
from 13 to 16 a day – 1 tablet 3 times a day, every 4 hours;
17 20 day – 1 tablet 3 times a day, every 5 hours
. 21 to 25 a day – 1-2 tablets a day
full smoking cessation should occur no later than 5 days from the start of treatment.
At the beginning of treatment possible: tachycardia, increased blood pressure, palpitations; headache, dizziness, insomnia or drowsiness, irritability; dyspnea; changes in taste and appetite, dry mouth, nausea, abdominal pain, constipation, diarrhea; myalgia; increased sweating, weight loss; pain in the chest. The drug is generally well tolerated, the observed side effects are mild or moderate. Most of them appear at the beginning of treatment and disappear on their own. They are most often associated with nicotine addiction.
Overdose Symptoms of overdose: nausea, vomiting, dilated pupils, weakness, tachycardia, clonic convulsions, respiratory paralysis. Treatment: gastric lavage, infusion administration of aqueous salt solutions and 5% or 10% glucose solutions, anticonvulsants, cardiotonics, a respiratory analeptic and other symptomatic agents. Monitors the breathing, blood pressure and heart rate.
Interaction with other drugs
Tsitizin should not be taken simultaneously with the drugs because of the risk of increasing its side effects. In an application winstrol results with winstrol results and anticholinesterase drugs may increase the side effects of cholinomimetic.
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Should be prescribed only if the patient has a serious intention to quit smoking. Treatment of drug and continued smoking may lead to increased side effects of nicotine (nicotine intoxication).
The drug contains the excipient lactose.
Patients with rare hereditary problems of galactose intolerance, with lactase deficiency (type Lapp) or glucose-galactose malabsorption should not use the drug.
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